Fr-TM-align: a new protein structural alignment method based on fragment alignments and the TM-score
نویسندگان
چکیده
منابع مشابه
TM-align: a protein structure alignment algorithm based on the TM-score
We have developed TM-align, a new algorithm to identify the best structural alignment between protein pairs that combines the TM-score rotation matrix and Dynamic Programming (DP). The algorithm is approximately 4 times faster than CE and 20 times faster than DALI and SAL. On average, the resulting structure alignments have higher accuracy and coverage than those provided by these most often-us...
متن کاملAccelerated protein structure comparison using TM-score-GPU
MOTIVATION Accurate comparisons of different protein structures play important roles in structural biology, structure prediction and functional annotation. The root-mean-square-deviation (RMSD) after optimal superposition is the predominant measure of similarity due to the ease and speed of computation. However, global RMSD is dependent on the length of the protein and can be dominated by diver...
متن کاملCAB-Align: A Flexible Protein Structure Alignment Method Based on the Residue-Residue Contact Area
Proteins are flexible, and this flexibility has an essential functional role. Flexibility can be observed in loop regions, rearrangements between secondary structure elements, and conformational changes between entire domains. However, most protein structure alignment methods treat protein structures as rigid bodies. Thus, these methods fail to identify the equivalences of residue pairs in regi...
متن کاملEnglish-Hungarian NP Alignment in MetaMorpho TM
In this paper, a fast automatic NP alignment technique developed for MetaMorpho TM is presented. MetaMorpho TM is an EBMT-based translation memory that stores not only full sentence pairs but also NP pairs in its database of translations. In order to fulfill speed requirements of a translation memory (segments have to be stored quickly), in the proposed NP alignment algorithm time consuming sta...
متن کاملA historical perspective on developing foundations iInfo(TM) information systems: iConsult(TM) and iEntertain(TM) apps using iDescribers(TM) information integration for iOrgs(TM) information systems
Technology now at hand can integrate all kinds of digital information for individuals, groups, and organizations so their information usefully links together. iInfoTM information integration works by making connections including examples like the following: A statistical connection between “being in a traffic jam” and “driving in downtown Trenton between 5PM and 6PM on a weekday.” A termino...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2008
ISSN: 1471-2105
DOI: 10.1186/1471-2105-9-531